Motif ID: MEF2{A,B,C,D}.p2

Z-value: 1.311


Transcription factors associated with MEF2{A,B,C,D}.p2:

Gene SymbolEntrez IDGene Name
MEF2A 4205 myocyte enhancer factor 2A
MEF2B 100271849 myocyte enhancer factor 2B
MEF2BNB-MEF2B 4207 MEF2BNB-MEF2B readthrough
MEF2C 4208 myocyte enhancer factor 2C
MEF2D 4209 myocyte enhancer factor 2D

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MEF2Dchr1_-_1564603900.613.6e-04Click!
MEF2Bchr19_-_19281090,
chr19_-_19281062
0.461.1e-02Click!
MEF2Achr15_+_100106214-0.291.2e-01Click!
MEF2Cchr5_-_881196040.144.6e-01Click!
MEF2BNB-MEF2Bchr19_-_19303222-0.086.6e-01Click!


Activity profile for motif MEF2{A,B,C,D}.p2.

activity profile for motif MEF2{A,B,C,D}.p2


Sorted Z-values histogram for motif MEF2{A,B,C,D}.p2

Sorted Z-values for motif MEF2{A,B,C,D}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MEF2{A,B,C,D}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_41742666 6.722 NM_002192
INHBA
inhibin, beta A
chr1_-_153029987 4.988 NM_005988
SPRR2A
small proline-rich protein 2A
chr10_+_118187381 4.300 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr1_-_153067000 4.132 NM_001024209
SPRR2E
small proline-rich protein 2E
chr1_+_84630575 4.076 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr1_-_153013593 3.182 NM_006945
SPRR2D
small proline-rich protein 2D
chr3_-_42843217 3.164


chr18_+_29027731 3.114 NM_001944
DSG3
desmoglein 3
chr1_+_151032683 2.772 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_151032880 2.761 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_151032866 2.727 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_-_153085963 2.712 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr12_+_8975149 2.673 NM_144670
A2ML1
alpha-2-macroglobulin-like 1
chr2_-_31352489 2.644 NM_001253827
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr2_-_211168315 2.638 NM_079422
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr12_+_15699277 2.553 NM_030668
NM_030669
NM_030670
NM_030671
PTPRO



protein tyrosine phosphatase, receptor type, O



chr1_+_152486977 2.443 NM_019060
CRCT1
cysteine-rich C-terminal 1
chr12_+_119616594 2.393 NM_014365
HSPB8
heat shock 22kDa protein 8
chr13_-_60325073 2.353


chr8_-_6735438 2.170 NM_005218
DEFB1
defensin, beta 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.27 3.42e-02 GO:0003012 muscle system process
1.22 2.60e-04 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
4.79 4.96e-02 GO:0001533 cornified envelope
3.36 4.34e-07 GO:0030016 myofibril
3.34 1.12e-05 GO:0030017 sarcomere
3.27 4.90e-07 GO:0043292 contractile fiber
3.23 4.07e-06 GO:0044449 contractile fiber part
1.85 3.07e-02 GO:0015629 actin cytoskeleton
1.82 4.60e-10 GO:0044421 extracellular region part
1.79 7.88e-07 GO:0005615 extracellular space
1.43 7.73e-06 GO:0005576 extracellular region

Nothing significant found in function category.